Isolation of an elastase inhibitor, (+)-gossypol from the bark of Thespesia populnea plant

نویسندگان

  • T. Annamalai
  • G. Venkateswara Rao
چکیده

Bioassay guided purification of methanolic extract of the bark of the plant, Thespesia populnea yielded a naphthalene derivative, (+)-gossypol (1). The structure of compound, (+)-gossypol has been established based on its physical and spectral data (UV, IR, H & C NMR and Mass). The compound has been shown moderate elastase inhibition activity when compared with control compound, ursolic acid.

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تاریخ انتشار 2013